A Question of Taste at the Centre for Life

A group of Sixth Form Biology students from Sacred Heart recently took part in an enriching educational experience at the Centre for Life. The session was carefully structured to deepen their understanding of genetics and evolution, providing an exciting opportunity to work with their own DNA.

The highlight of the visit was undoubtedly the hands-on laboratory work putting the learning into context. In a state-of-the-art lab, students applied modern molecular biology techniques to their own DNA. The process began with DNA extraction.  Using micropipettes, they carefully measured and transferred DNA samples in preparation for polymerase chain reaction (PCR), a crucial technique in molecular biology that amplifies DNA to allow for detailed gene analysis. Their focus was on a gene responsible for a bitter taste receptor called PTC.

Following amplification, the DNA underwent restriction enzyme digestion—a process that cuts DNA at specific sequences—before being analysed using gel electrophoresis. This technique, which separates DNA fragments based on size, enabled students to visualize their genotype and allowed them to compare this with their phenotype; whether they could taste the bitter compound or not. 

The day also involved an engaging discussion, with guidance from experts, where students explored the concept of convergent evolution, observing how different species can independently develop similar traits in response to comparable environmental pressures. This foundational knowledge helped bridge the gap between theoretical genetics and its real-world applications.

By the end of the day, students found the experience both engaging and informative. Not only did they gain valuable practical skills and knowledge, but they also developed a deeper appreciation for the possibilities and challenges within genetic research. This visit showcased the power of hands-on learning, reinforcing that when students actively engage with science, the lessons learned are both meaningful and long-lasting. A huge thank you to the Centre for Life for providing such an inspiring session!